Ketones, B-hydroxybutyrate (BHB), acetoacetate (ACA) and acetone, are the by-products of fat breakdown. Ketones can be used by the tissues, including the brain, in the body in much the same way as glucose, and are thought to be a superior fuel source to glucose. Being in a state of ketosis refers to having elevated blood levels of ketones.
Why would I take KETO//OS ?
Supplementing with exogenous ketones allows you to experience ketosis - the benefits of elevated blood ketone levels, without having to follow such a restrictive ketogenic diet, or super low carb diet, which is often difficult for some people to adhere to. Optimize your human potential.
How do I take the product ?
Dissolve 1 heaping scoop or OTG pack in 12-16oz. of cold water and shake/stir vigorously. Can be taken with or without food. • Therapeutic serving = 1 daily serving • Optimal performance = 2 servings AM/PM
Can children take KETO//OS ?
Yes, children can also take KETO//OS, however the serving would have to be adjusted for the age/weight of the child.
What serving size of KETO//OS should I start with?
Start slowly: We recommend everyone begin with 1/2 serving of KETO//OS because MCT oils (healthy fats) in the product are quickly absorbed. For some, this can cause very temporary GI (Gastrointestinal) discomfort. If this is the case, repeat Day 1 until your body is acclimated or start with a 1/4 serving. It's important to hydrate: Drink 12 oz. of plain water before mixing KETO//OS or first thing in the morning.
What kind of diet should I follow when I’m taking KETO//OS ?
The wonderful thing about taking exogenous ketones via KETO//OS is that you can experience the benefits of ketones without diet modification. Even those who don’t change a thing, will still experience the benefits. However, it is encouraged that you slowly begin to follow a lower carbohydrate diet, and enhance your body’s ability to utilize. Follow the 8 steps in the N8tive OS-Zone to get you on the right track.
Does KETO// OS have any side effects ?
Supplementing with KETO//OS or following a ketogenic diet can cause a slightly diuretic effect, and can deplete magnesium, potassium and sodium stores. This can be rectified by supplementing with a good electrolyte or increasing the sodium in your diet. However KETO//OS adds additional sodium to the formulation to counter-act this sodium depletion. The first signs of dehydration are fatigue, headache, dizziness, dry mouth, swollen tongue, constipation, possible elevation of blood pressure, palpitations or muscle cramping. If this occurs, decrease your serving size of Uncharged Keto//OS or BioMax, drink plenty of water. KETO//OS 2.1 and Keto Kreme is blended with medium chain triglycerides, which can often times cause digestive distress. This is due to the fact that your body has not yet adapted to the increased fats in your diet, and is less efficient at utilizing ketones as its fuel source. Once the body has adapted to this increased fat in the diet, the digestive distress should resolve. We recommend to start slowly with a reduced serving size and build up to a full serving twice a day, but it is totally up to the individual. If diarrhea, stomach cramping or constipation occur, reduce your serving size of Keto//OS and/or consume Keto//OS with food (fat or protein) until bowel movements have returned to normal. Do not increase Keto//OS if you are experience digestive stress. Please make sure that you are drinking enough water and taking a multi-mineral supplement or an/ electrolyte. Experiencing Diarrhea and cramping then decrease Keto//OS, drink slower (over 20-30minutes) and consume with food. This will slow down the absorption of the exogenous ketones. Do not increase Keto//OS until bowel movements have returned to normal and use the uncharged version. Experiencing constipation, reduce the servings size, drink slower (over 20-30minutes), take a magnesium/multi-mineral supplement and drink plenty of water. the major function of the large intestine is to reabsorb water. Do not increase Keto//OS until bowel movements have returned to normal.
What are B HB Salts and where do they come from?
BHB is found in nature in many foods including eggs and milk. Salts are acids and bases bound by ionic bonds. Salt is a chemistry term used to describe a specific type of chemical compound. Technically, they are defined as ionic compounds formed by the neutralization of an acid and a base. They consist of positively charged and negatively charged components, which typically dissociate in water or water-based solutions (such as blood). In lay terminology, we call table salt, which is actually sodium chloride (NaCl) “salt,” but it is just one of many chemical compounds which are defined as salts. The “BHB salt” is simply a compound that consists of sodium (Na+), potassium (K+), and the ketone body β-hydroxybutyrate. In the Keto OS product package, these individual components are being held together by ionic bonds; however, when you eat the product, it is absorbed into the blood where it dissociates into free Na+, K+, and BHB since it is a water-based solution. Thus, consuming the product directly and immediately puts ketones into your blood. Ketones are naturally slightly acidic, so the combination of BHB with sodium acts as a bit of a buffer to this acidity. Ketones will also naturally act as a diuretic, so you lose salt, potassium calcium and magnesium, and it is generally encouraged to increase sodium intake with ketones. The addition of sodium to the product will replenish this salt loss.
Ketosis & the Ketogenic Diet.
What is a ketogenic diet and how does it work? The process was initially developed in 1924 by Dr. Russell Wilder as an effective, non-pharmacological treatment for intractable childhood epilepsy. The process works when the body is put into a metabolic state called Ketosis, where ketones become the main source of energy for the brain and body to function. The ketogenic diet plan is high in fat and low in carbohydrates while supplying adequate protein to the body. This specific combination changes the manner in which your body uses energy. Additionally, while reducing epileptic seizures, this process lowers glucose levels while improving the body’s resistance to insulin.
How Does Ketosis Work and what is Ketosis ?
It is when your body goes through a metabolic state in which the body transforms ketones created from fat into energy, instead of energy created from converting carbohydrates. Biochemically speaking, ketones are organic, carbon-based compounds that contain a central carbon atom double-bonded to an oxygen atom and two carbon-containing substituents, denoted by “R.” Ketones are considered simple compounds because they do not contain chemical groups that are readily reactive. Fatty acids in the body are oxidized by the liver for energy production.
There are 3 different ketone bodies produced in mitochondria of the liver:
Some of these fatty acids are oxidized by the liver for energy production while others can be partially oxidized to form the substrate acetoacetate, which is then converted to beta-hydroxybutyric acid; collective. These bodies produced in the liver are referred to as endogenous ketone bodies and are those ingested through nutritional supplements.
How Does It Effect Our Liver ?
While our livers produce endogenous ketone bodies, it is these bodies that also provide the user with an instant supply of ketones to utilize, even if your body is not in a state yet. When consuming a low-carb diet, the levels of the hormone insulin are reduced and in turn, fatty acids are released from the fat stores in our body. Glucose levels drop, Lipase releases stored triglycerides and these are the fatty acids transferred to the liver and oxidized into ketones. When they are created, they can then be used by all the tissues containing mitochondria, including the muscles and brain. Unlike fatty acids, they have the unique ability to cross the blood-brain barrier to provide energy to the brain in the absence of glucose. The process naturally occurs during pregnancy, infancy, fasting and starvation. The benefits are numerous as it not only reduces epileptic seizures but leads to weight loss and lower blood sugar levels.
What Do I Have to Do to Reach a Full State of Ketosis ?
In order for the body to go into a state of ketosis, people must follow a very strict diet menu, which involves consuming less than 50 grams of carbs per day and sometimes as little as 20 grams per day. In order to achieve this, certain foods must be eliminated from your diet so that you are following a strict meal plan, removing all sweets, candy, cookies, soft drinks and desserts. Other carbohydrate-rich foods that should be avoided are bread, cereals, rice and potatoes. Stricter forms of this special meal plan should also include pasta on this list. In the classic version of the diet, fats should comprise 60 to 70 percent of your daily caloric intake. Proteins should be around 20 to 30 percent and carbohydrates should not exceed 50 grams per day. Someone consuming a "traditional Western diet" has a blood ketone level that's typically around 0.1 to 0.2 mmols.
However, when constricting yourself to a true ketogenic diet plan, the menu on this particular diet can look something like 75 percent fats, 20 percent protein and 5 percent carbs—your blood ketones can raise to somewhere between 0.5-5.0 mmols, putting you in a state of "nutritional ketosis.” There are numerous studies that have come to the conclusion in their research that high-fat diets result in obesity, high levels of bad cholesterol can lead to resistance to insulin and cardiovascular disease. These ketogenic meal plans, however, are not just high-fat diets, they are actually high-fat, low-carb diets and this is an important distinction. A typical persons diet of high-fat, high carb intake usually leads to many health problems. According to research conducted by Robert R. Wolfe, after conducting a keto blood test, they found that when they injected fat directly into the bloodstream, the fat was used as fuel. When the researchers infused the fat along with carbohydrates, they discovered that the fat was prevented from being converted into fuel and the resistance to insulin began. The conclusion was they discovered that fats rely on an enzyme known as CPT1 to transport them into the mitochondria of cells. When high amounts of insulin are present, they act an inhibitor, preventing the transport and preventing the oxidation of fat. This is the reason that ketogenic diet works, for it requires a very low level of carbohydrates as not to impede the process of fats being turned into energy.
What is a ketogenic diet and how does it work?
The process was initially developed in 1924 by Dr. Russell Wilder as an effective, non-pharmacological treatment for intractable childhood epilepsy. The process works when the body is put into a metabolic state called Ketosis, where ketones become the main source of energy for the brain and body to function. The ketogenic diet plan is high in fat and low in carbohydrates while supplying adequate protein to the body. This specific combination changes the manner in which your body uses energy. Additionally, while reducing epileptic seizures, this process lowers glucose levels while improving the body’s resistance to insulin.
What Foods to Eat?
Dark Meat of Chicken
Lard / Tallow
Fish / Fish Oil
Organic Whipping Cream
Avocado / Avocado Oil(no Frying)
Olives / Olive Oil
Macadamia Nut (small amounts)
Macadamia Oi; (no Frying)
Coconut-Mlk Butter- Oil- Flour
Flax Meal / Flax Oil
Dark Meat of Chicken
Lard / Tallow
Low Glycemic Veggies:
Dark Leafy Greens
What's a Ketogenic Diet Plan?
what a ketogenic diet menu looks like, and what the diet foods are, as well as how much of it each day you should be having is crucial to reaching your ketosis best goals. So you've heard about the benefits, weighed up the challenges and you've decided you're going all in. Congratulations.
Now I bet you want to know what exactly goes into a keto diet, what the different types of foods you can eat and what you're diet plan will look like. Well, we're actually working on a full ketogenic diet plan guide for you guys as we speak, but in the meantime, I'll just quickly break down the basics for you here.
Here are the main food groups in a ketogenic diet meal plan:
Fats and Oils - Try to get your fat from natural sources like meats and nuts. Supplement with saturated and monounsaturated fats like coconut oil, butter and olive oil.
Protein - Try to stick with organic, grass-fed meat where possible. It is important to remember that too much protein on a keto diet isn't a good thing.
Vegetables - Try to stick with above ground vegetables, leafy and green is always best. Fresh or frozen it doesn't matter.
Dairy - Full fat dairy products
Nuts and seeds - Only in moderation.
Beverages - Keep simple, and try to stick to mostly water. You can flavor water with lemon or limes.
Ok, so here is a simplified list of the foods you can eat, but how much of each should you be having? That's why counting your macronutrients is apart of the game, when you're delving into this world. If you don't like counting macros, then this isn't for you.
When it comes to consumption, here's how the macros end up looking like for most people: Carbohydrates: 5-10% Fats: 70-75% Protein: 15-20%
Obviously, there is a lot to discuss when it comes to this subject, which is why we thought we would create a complete guide dedicated to explaining the keto diet plan and what it involves exactly. But in a nutshell, this is what your nutritional lifestyle might look like if you choose to proceed.
Main Benefits of a Ketogenic Diet Plan?
There are so many benefits to adopting a ketogenic diet into your lifestyle, the main one being the body’s ability to utilize fats for fuel. Studies in the field of nutrition have led many to believe that a high carb diet is essential for maintaining energy levels and endurance. However, in a study conducted in 2004 by Stephen D Phinney, the conclusions presented seemed to clarify the difference between a ketogenic diet vs. a high carb diet on test subjects both athletically training and on patients that did not train.
His conclusions stated: “Both observational and prospectively designed studies support the conclusion that submaximal endurance performance can be sustained despite the virtual exclusion of carbohydrate from the human diet." Clearly, this result does not automatically follow the casual implementation of nutritional carbohydrate restriction, however, as careful attention to time for keto-adaptation, mineral nutrition and constraint of the daily protein dose is required. Contradictory results in the scientific literature can be explained by the lack of attention to these lessons learned (and for the most part now forgotten) by the cultures that traditionally lived by hunting.
Therapeutic use of this diet should not require constraint of most forms of physical labor or recreational activity, with the one caveat that anaerobic (i.e., weight lifting or sprints) performance is limited by the low muscle glycogen levels induced by a ketogenic diet and this would strongly discourage its use under most conditions of competitive athletics. “ When a person is on a high carb diet, the body expects energy to keep entering the system whereas, with a ketogenic diet plan, the body becomes efficient transforming fats into energy.
How Ketones Help Reduce The Rate at Which Cancer Tumors Grow
Studies show that constricting yourself to these certain foods also increases the efficiency of all your other cells. Cancer cells behave differently than other cells as something in the regulatory mechanism breaks down and they start growing and dividing rapidly. The cancerous cells then start hoarding energy from the blood while manipulating their surroundings in order to grow and support that rapid growth. These cells produce and multiply with fermentation which requires glucose, so by limiting this; you are taking away that fuel they need to grow and survive. Although it doesn’t prevent the cells from sapping energy from gluconeogenesis, it will aid in cutting off a source of fuel for them to grow faster. Any type of low carb regime like this diet lowers blood levels of the hormone insulin and IGF-1. This reduction results in theses cancer cells receiving less signals to grow and divide. Ketone bodies have been shown to inhibit the growth of cancer cells in cultures. Certain instances of patients with tumors, when put on a ketogenic diet plan and limiting their carb intake, had positive effects on their treatment and cure. The tumors stopped growing or became indolent which made the cells vulnerable to treatments and therapeutic drugs. A study in 2012 on 10 advanced Cancer patients yielded some promising results. The patients took part in a low-carb ketogenic meal plan for approximately 28 days. After the trial ended, 4 out of the 10 patients still continued to have the disease progress, while 5 remained stable and 1 had a partial remission. The patients on this diet plan that had the highest ketone levels and the lowest insulin levels improved the most. A study conducted in 2014 by Bryan G. Allen and other researches yielded some interesting results and theories as to future treatments. In their findings, they state that “ keto foods have been studied as an adjuvant to cancer therapy in both animal models and human case reports. As early as 1987, Tisdale et al. saw decreased tumor weight and improved cachexia in mice with colon adenocarcinoma xenografts after eating the foods allowed on this diet. Additional studies have shown that this diet has reduced tumor growth and improve survival in animal models of malignant glioma and colon cancer, gastric cancer and prostate cancer. Furthermore, it has been hypothesized, with some supporting evidence, to potentiate the effects of radiation in malignant glioma models as well as in non-small cell lung cancer models. Fasting, which also induces a full state of ketosis and has been shown to enhance responsiveness to chemotherapy in pre-clinical cancer therapy models as well as possibly ameliorating some of the normal tissue side-effects seen with chemotherapy. Fasting cycles are also reported to retard the growth of tumors and sensitize a range of cancer cell types to chemotherapy.”
During this same study, the researchers noted that in a case study with two female pediatric patients with advanced staged malignant astrocytoma, demonstrated a 21.8% decrease in tumor SUV when put on this ketogenic diet plan. It was also noted that there were no long-term severely adverse effects on the diet and it actually reduced insomnia in the patients and improved their emotions. In their conclusions of this study, they note that the current treatments for cancer via chemo-radiation lead to serious adverse effects on the body. This outlines a need for less toxic treatments with adverse effects that enhance the response to cancerous cells vs. normal tissues.
Another study was conducted in a 12 week period on 16 advanced-stage cancer patients and it was found in the research that a ketogenic diet vastly improved the quality of life and actually stopped the progression of cancer for the 5 patients who completed the study. In 2010, a study conducted by Robert Krikorian and other researchers revealed that nutritional ketogenic meal plans improved the memory in patients with mild cognitive impairment. The research was conducted on 23 older adults afflicted with mild cognitive impairment. They were given either a high-carb diet or a very low-carb ketogenic diet. Over a 6 week span, they observed an improvement of verbal memory performance from the subjects on the low-carb diet. This as well as a reduction in weight, fasting glucose and fasting insulin. They discovered that ketone levels were directly correlated with memory. Low carb consumption, even in short term periods, can improve memory function in elderly adults with increased risk of Alzheimer’s disease.